Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series?

نویسندگان

  • Thomas L Diepgen
  • Derk P Bruynzeel
  • Klaus E Andersen
  • Francisco M Brandão
  • Magnus Bruze
  • Margarida Gonçalo
  • An Goossens
  • Arto Lahti
  • Vera Mahler
  • Torkil Menné
  • Ian R White
  • John D Wilkinson
چکیده

Mercaptobenzothiazole (MBT) compounds are well known contact allergens. To detect rubber allergic patients we use both MBT (2% in petrolatum) and a mercapto-mix with 4 constituents of 0.5% each in our standard series. In this article the EECDRG presents data of in total 32,475 consecutive tested patients attending the respective contact dermatitis clinics from 11 centres in Europe to determine if the mix and MBT detected the same allergic patients. We found 327 patients positive to the mix or MBT, or to both. 261 were positive to the mix and 254 to MBT. MBT was negative in 73 patients who were positive to the mix. If the mix had not been in the standard series, on average 22% of patients allergic to a mercapto-compound would have been missed, for MBT this would have been on average 20%. All clinics would have missed a significant number of positive reactions if both compounds had not been tested. We conclude, that both the mercapto mix and MBT are required in the standard series.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Spectrophotometric Determination of 4-Hydroxy-2-mercapto-6-methylpyrimidine Based on Aggregation of Colloidal Gold Nanoparticles

We report herein the development of a highly sensitive colorimetric method for the detection of 4-hydroxy-2-mercapto-6-methylpyrimidine (MTU) which acts as an anti-thyroid drug utilizing citrate capped gold nanoparticles (Au-NPs). This thiol-containing molecule exhibits intriguing affinity with Au-NPs. The reactivity involves the displacement of the citrate shell by the thiolate shell followed ...

متن کامل

Strategic Analysis of Sports Tourism Marketing Mix in Mazandaran with 7P's Approach

The development and improvement of the tourism industry in the country or its various regions depends on effective marketing mechanisms. Marketing is an instrument for promoting sport tourism in different regions, which should be carefully considered. The purpose of this study was to analyze the strategic combination of sports tourism marketing in Mazandaran province with a 7 P's approach. 235 ...

متن کامل

Frequency of contact sensitization to European Standard Series (ESS) in contact and/or atopic dermatitis patients in Rasht, Ahwaz, Kerman and Hamedan

Background and aim: The frequency of sensitization to contact allergens varies in different countries because of both genetic and, more importantly, allergen exposure variations. The objective is to determine the frequency of sensitization to contact allergens in Iranian patients with dermatitis.Materials and methods: Four hundreds and one patients with a clinical diagn...

متن کامل

Effects of Mix Cropping of Alfalfa and Annual Ryegrass on Forage Production

Mix cropping of alfalfa (Medicago sativa) and annual ryegrass (Lolium rigidum) may improve forage production in the rangeland and field conditions, especially in spring after the establishment year. In this study, the effects of different sowing rates of alfalfa and annual ryegrass seeds in the replacement and additive series of mix cropping were evaluated on forage yield in first year after th...

متن کامل

Case study of the statistical distribution of the concretes implemented at Qazvin

Characteristics of produced concrete become changedthrough changingthe characteristics of materials constituting the concrete. These changes include: The quality of cement, the real ration of water to cement: with neglecting the further water within the aggregates or lack of that, the consideredratio fluctuates and the characteristics of the aggregate which are related to the following dimensio...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Contact dermatitis

دوره 55 1  شماره 

صفحات  -

تاریخ انتشار 2006